Intermediaries like methyl phenyl butane and sulphonamido phenyl hydrazine hydrochloride is used in synthesis celecoxib. Methylthio acetophenone is used in synthesis vioxx (rofecoxib) and other new drugs. These intermediaries are largely used for osteoarthritis and rheumatoid arthritis. For osteoporosis intermediates like acetyl pyridine and for diabetes thiazolidine dione is used. Erythromycin oxime is a drug intermediate often used for azithromycin, roxithromycin, and clarithromycin. N,n'-dibenzyl ethylenediamine diacetate is an ideal intermediate used in manufacturing of benzathine penicillin. Ortho chlorobenzylamine is used to manufacturing ticlopidine. Tetrachloroethyl chloroformate is an intermediate used to protect reagent for alcohol. Diphenyl prolinol is used for asymmetric reduction of ketones to chiral alcohol.

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